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Lymphoma: Symptoms, Types, Diagnosis, and Treatment

Lymphoma: Symptoms, Types, Diagnosis, and Treatment

Posted by Pankaj Dhiman on Sep 5th 2023


Everything You Need to Know About Lymphoma


Lymphoma is a cancer of the lymphatic system, which is part of the immune system. The lymphatic system is a network of tissues and organs that help the body fight infection. Lymphoma can affect people of all ages, but it is most common in adults over the age of 50.


Symptoms of Lymphoma


The symptoms of lymphoma can vary depending on the type and stage of the cancer. Some common symptoms include:

  • Swollen lymph nodes, especially in the neck, armpit, or groin
  • Fever
  • Night sweats
  • Fatigue
  • Weight loss
  • Itching
  • Easy bruising or bleeding
  • Cough
  • Shortness of breath
  • Pain in the chest or abdomen
  • Enlarged spleen
  • Bone pain

  1. Swollen Lymph Nodes, especially in the neck, armpit, or groin: Lymph nodes are small, bean-shaped structures that are part of the lymphatic system. Swelling of lymph nodes is often one of the first signs of lymphoma. This can manifest as painless lumps or bumps in areas like the neck, underarms, or groin.
  2. Fever: Unexplained and persistent fever is a symptom that can be associated with lymphoma. The fever might come and go and could be low-grade or high-grade.
  3. Night Sweats: Night sweats refer to excessive sweating during the night, to the point where you wake up drenched in sweat. They can be quite severe and disrupt sleep. Night sweats are a common symptom of lymphoma.
  4. Fatigue: Fatigue is a persistent feeling of tiredness or lack of energy that doesn't improve with rest. It can be a common symptom in lymphoma patients, often due to the body's immune response and the cancer's impact on overall health.
  5. Weight Loss: Unexplained and unintentional weight loss can be a sign of lymphoma. Patients may lose a significant amount of weight without making changes to their diet or exercise routines.
  6. Itching: Pruritus, or itching, can be experienced by lymphoma patients, often without an obvious cause. It can affect the skin and be generalized or localized.
  7. Easy Bruising or Bleeding: Lymphoma can affect blood cell production, leading to a decrease in platelets. This can result in easy bruising or bleeding, even with minor injuries.
  8. Cough: A persistent cough can be a symptom of lymphoma if the cancer affects the lymph nodes in the chest or if it spreads to the lungs.
  9. Shortness of Breath: If lymphoma affects the lymph nodes in the chest, it can compress the airways or blood vessels, leading to shortness of breath.
  10. Pain in the Chest or Abdomen: Pain in these areas can occur if lymphoma involves nearby structures. For example, chest pain might arise if lymph nodes in the chest become enlarged, and abdominal pain might be a result of enlarged lymph nodes or spleen in the abdominal area.
  11. Enlarged Spleen: An enlarged spleen, known as splenomegaly, can occur in lymphoma. This may lead to discomfort or pain in the upper left side of the abdomen.
  12. Bone Pain: Lymphoma can sometimes involve the bone marrow or nearby bones, leading to bone pain. This pain can be persistent and is typically localized to specific areas.

It's important to note that these symptoms can also be caused by various other medical conditions, and the presence of these symptoms does not necessarily mean a person has lymphoma. However, if you or someone you know is experiencing these symptoms, it's essential to consult a healthcare professional for a thorough evaluation and diagnosis. Early detection and treatment of lymphoma can significantly improve outcomes.


Where is Lymphoma Found?


Lymphoma can be found anywhere in the lymphatic system, including the lymph nodes, spleen, thymus, and bone marrow. It can also spread to other organs, such as the lungs, liver, and brain.


Symptoms of Lymphoma in Children


The symptoms of lymphoma in children are similar to the symptoms in adults, but they may also include:

  • Painless enlargement of the liver or spleen
  • Bone pain
  • Easy bruising or bleeding
  • Enlarged tonsils
  • Rash
  • Fever
  • Night sweats
  • Fatigue

Diagnosis of Lymphoma


The diagnosis of lymphoma is made by a doctor who will perform a physical exam and order blood tests, imaging tests, and a biopsy. Blood tests can help to rule out other conditions, and imaging tests can help to determine the size and location of the lymphoma. A biopsy is a procedure in which a small piece of tissue is removed from the lymph node or other affected area and examined under a microscope by a pathologist.


Treatment for Lymphoma


The treatment for lymphoma depends on the type and stage of the cancer. Treatment options may include:

  • Chemotherapy
  • Radiation therapy
  • Bone marrow transplant
  • Targeted therapy
  • Immunotherapy

Outlook for Lymphoma


The outlook for people with lymphoma depends on the type and stage of the cancer, as well as the patient's age and overall health. The overall survival rate for people with Hodgkin lymphoma is over 80%. The outlook for people with non-Hodgkin lymphoma is more variable, but the survival rate for many subtypes is also high.


FAQs about Lymphoma


Q. What are the risk factors for lymphoma?

A. The risk factors for lymphoma include:

  • Age (over 50) 
  • Family history of lymphoma 
  • Exposure to certain chemicals, such as herbicides and pesticides 
  • Certain autoimmune diseases, such as rheumatoid arthritis and lupus
  • HIV/AIDS

Q. Can lymphoma be prevented?

A. There is no sure way to prevent lymphoma, but there are some things you can do to reduce your risk, such as:

  • Avoiding exposure to certain chemicals 
  • Getting regular checkups 
  • Eating a healthy diet 
  • Exercising regularly 
  • Managing stress

Q. What are the latest advances in the treatment of lymphoma?

A. There have been many advances in the treatment of lymphoma in recent years. Newer treatments, such as targeted therapy and immunotherapy, are more targeted and have fewer side effects than traditional treatments, such as chemotherapy and radiation therapy.